Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
Vitronectin, Human Plasma recombinant protein
S- protein, Serum-spreading factor, V75
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P04004 |
|---|---|
| Concentration | 0.2 to 0.4 |
| Calculated MW | 75.0 kDa |
| Gene ID | 7448 |
|---|---|
| Gene Symbol | VTN |
| Other Names | S- protein, Serum-spreading factor, V75 |
| Gene Source | Human |
| Source | Human plasma |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | HPLC; |
| Recombinant | No |
| Target/Specificity | Vitronectin |
| Application Notes | Reconstitute in H₂O or aqueous buffers to a concentration not less than 0.1 mg/ml. Aliquot and store at –20°C. Avoid freeze-thaw cycles. |
| Format | Lyophilized protein |
| Storage | -20°C; Lyophilized from 10 mM sodium phosphate, pH 7.7 |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Vitronectin and plasminogen activator inhibitor type 1 are proteins that interact in the circulatory system and pericellular region to regulate fibrinolysis, cell adhesion, and migration. Plasminogen activator inhibitor type 1, a serine proteinase, through its binding to the plasma protein vitronectin, influences processes that are key regulators of hemostatic process, for example, thrombosis and wound healing. In addition, the vitronectin and plasminogen activator inhibitor type 1 complex regulates binding of blood platelets and cells to extracellular substrata in events like tumor metastasis. The plasma concentration of vitronectin is 200 to 400 µg/ml.
References
Suzuki S.,et al.EMBO J. 4:2519-2524(1985).
Suzuki S.,et al.Submitted (JUN-1986) to the PIR data bank.
Jenne D.E.,et al.EMBO J. 4:3153-3157(1985).
Jenne D.E.,et al.Biochemistry 26:6735-6742(1987).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
