|Calculated MW||12.7 kDa|
|Other Names||NC30, ALRH, BHR1, P600, IL-13, MGC116786, MGC116788, MGC116789.|
|Application Notes||Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can be diluted into other aqueous buffers|
|Storage||-20°C; Sterile filtered and lyophilized with no additives|
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Provided below are standard protocols that you may find useful for product applications.
IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having similar structural features and functional characteristics as IL-4, but only shares ~30% homolog with the IL-4 sequence. IL-13 inhibits IL-1β, IL-6, IL-8, and TNF-α resulting in anti-inflammatory effects on monocytes and macrophages. IL-13 also induces B cells to proliferate and modulating TH2 cell development. Recombinant rat IL-13 is an 11.9 kDa protein containing 109 amino acid residues.
Lakkis F.G.,et al.Biochem. Biophys. Res. Commun. 197:612-618(1993).
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