|Calculated MW||33.8 kDa|
|Other Names||Interleukin 17E, Interleukin-25,|
|Application Notes||The lyophilized IL-17E can be reconstituted in H₂O to a concentration of 0.1 µg/ µl. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.|
|Storage||-20°C; Lyophilized with no additives|
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Provided below are standard protocols that you may find useful for product applications.
IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NK-kB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains.
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