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MCP-4, human recombinant protein
Monocyte Chemotactic Protein-4, CCL13, NCC-1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q99616 |
|---|---|
| Calculated MW | 8.6 kDa |
| Gene ID | 6357 |
|---|---|
| Gene Symbol | MCP4 |
| Other Names | Monocyte Chemotactic Protein-4, CCL13, NCC-1, Small-inducible cytokine A13 |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | HPLC; ≥95% |
| Recombinant | Yes |
| Results | 10-100 ng/ml. |
| Target/Specificity | MCP-4 |
| Application Notes | Reconstitute in H₂O to a concentration of not less than 0.1 mg/ml. This solution can be diluted into other buffered solutions or stored at –20°C for future use. |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered and then lyophilized from a concentrated (1mg/ml) sterile solution containing 20 mM phosphate buffer, pH 7.4 and 130 mM NaCl. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Human macrophage/monocyte chemotactic protein-4 (MCP-4) is a member of the β chemokine family (C-C) of cytokines. Like eotaxin, MCP-4 is a powerful eosinophil chemoattractant. Additionally, like MCP-3, MCP-4 elicits chemoattraction of monocytes and T lymphocytes. MCP-4 is a peptide of 8.6 kDa that consists of 75 amino acid residues.
References
Power C.A.,et al.Eur. Cytokine Netw. 7:513-513(1996).
Garcia-Zepeda E.A.,et al.J. Immunol. 157:5613-5626(1996).
Uguccioni M.,et al.J. Exp. Med. 183:2379-2384(1996).
Berkhout T.A.,et al.J. Biol. Chem. 272:16404-16413(1997).
Godiska R.,et al.J. Leukoc. Biol. 61:353-360(1997).
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