Osteoprotegerin (OPG), human recombinant protein
Osteoprotegerin, OPG
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O14788 |
|---|---|
| Calculated MW | 20.0 kDa |
| Gene ID | 8600 |
|---|---|
| Gene Symbol | OPG |
| Other Names | Osteoprotegerin, OPG, Tumor necrosis factor receptor superfamily member 11B, Osteoclastogenesis inhibitory factor, TNFRSF11B, OCIF |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥98% |
| Assay2&Purity2 | HPLC; ≥98% |
| Recombinant | Yes |
| Results | 10 ng/ml |
| Target/Specificity | Osteoprotegerin |
| Application Notes | Reconstitute in 5 mM Tris, pH 7.5 to a concentration of 0.1-1.0 mg/ml. The solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use. |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered and then lyophilized |

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Provided below are standard protocols that you may find useful for product applications.
Background
Human OPG (Osteoprotegerin), also known as OCIF (Osteoclastogenesis inhibitory factor), is a member of the TNF receptor superfamily. Recombinant human OPG/OCIF specifically acts on bone tissues and increases bone mineral density and bone volume associated with a decrease of active osteoclast number. Recombinant human OPG is a 20 kDa protein, comprising of 174 amino acid residues.
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