|Calculated MW||102963 Da|
|Other Names||Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO.|
|Application Notes||Reconstitution in purified H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use. For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA).|
|Storage||-20°C; Lyophilized with no additives|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
TPO (Thrombopoietin, also known as Mpl-ligand, MGDF) stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant human TPO is a fully biologically active 174 amino acid polypeptide, which contains the erythropoietin-like domain of the full length TPO protein.
Kimura S.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:5555-5559(1987).
Libert F.,et al.Nucleic Acids Res. 15:6735-6735(1987).
Kimura S.,et al.Biochemistry 28:4481-4489(1989).
Barnett P.S.,et al.Nucleic Acids Res. 18:670-670(1990).
Rapoport B.,et al.Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.