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TPO, murine recombinant protein
Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl li
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P40226 |
|---|---|
| Calculated MW | 18.7 kDa |
| Gene ID | 21832 |
|---|---|
| Gene Symbol | TPO |
| Other Names | Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO. |
| Gene Source | Mouse |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥98% |
| Assay2&Purity2 | HPLC; ≥98% |
| Recombinant | Yes |
| Results | < 1.0 ng/ml |
| Target/Specificity | TPO |
| Application Notes | Reconstitute in H₂O to a concentration of 0.5-1.0 mg/ml. Further dilutions of this solution should be made into buffer containing carrier protein or medium containing serum. This solution can be stored at 4°C for 1 week or –20°C for future use. |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered and lyophilized from 10 mM Tris, pH 8.0 |
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Provided below are standard protocols that you may find useful for product applications.
Background
TPO (Thrombopoietin, also known as Mpl-ligand, MGDF) stimulates the proliferation and maturation of megakaryocytes and promotes increased circulation levels of platelets in vivo. The murine TPO is a soluble 18.7 kDa protein containing 174 amino acid residues, which comprises the receptor binding domain of the Mpl-ligand protein.
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