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Leptin, human recombinant protein
OB Protein, Obesity Protein, OBS, Obesity factor.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P41159 |
|---|---|
| Calculated MW | 16.0 kDa |
| Gene ID | 3952 |
|---|---|
| Gene Symbol | LEP |
| Other Names | OB Protein, Obesity Protein, OBS, Obesity factor. |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥98% |
| Assay2&Purity2 | HPLC; ≥98% |
| Recombinant | Yes |
| Target/Specificity | Leptin |
| Application Notes | Add 15 mM sterile HCl (0.5 ml/1 mg vial or 5 ml/10 mg vial) to the vial. After the protein is completely dissolved, add 7.5 mM sterile NaOH (0.3 ml/1 mg vial or 3 ml/10 mg vial) to bring the pH to approximately 5.2. |
| Format | Lyophilized protein |
| Storage | -20°C; Sterile filtered and lyophilized |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and seems to be involved in appetite control. The ob gene is expressed in adipose tissue and is thought to regulate the body’s fat stores. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Human Leptin is a 16 kDa protein containing 146 amino acid residues.
References
Zhang Y.,et al.Nature 372:425-432(1994).
Zhang Y.,et al.Nature 374:479-479(1995).
Masuzaki H.,et al.Diabetes 44:855-858(1995).
Gong D.W.,et al.J. Biol. Chem. 271:3971-3974(1996).
Chehab F.F.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
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