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IL-27b / EBI-3, human recombinant protein
Epstein-Barr virus induced 3, EBI3, IL25
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q14213 |
|---|---|
| Calculated MW | 23.3 kDa |
| Gene ID | 10148 |
|---|---|
| Gene Symbol | EBI3 |
| Other Names | Epstein-Barr virus induced 3, EBI3, IL-27 |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥90% |
| Assay2&Purity2 | HPLC; ≥90% |
| Recombinant | Yes |
| Target/Specificity | EBI-3/IL-27 |
| Application Notes | When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile H₂O at a concentration of 0.1 – 0.5 mg/ml, which can be further diluted into other aqueous solutions. |
| Format | Lyophilized protein |
| Storage | -20°C; Lyophilized with mannitol |
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Provided below are standard protocols that you may find useful for product applications.
Background
Epstein-Barr Virus Induced Gene-3 (EBI-3), is a secreted glycoprotein belonging to the hematopoietin receptor family and related to the p40 subunit of IL-12. It was identified by its induced expression in B-lymphocytes in response to Epstein-Barr virus infection. EBI-3 forms heterodimers with p28 to form IL-27 and with p35 to form IL-35. Both IL-27 and IL-35 have anti-inflammatory and regulatory activity. Recombinant Human EBI is a non-glycosylated polypeptide chain consisting of 209 amino acids with a molecular weight of 23.3 kDa
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