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>   home   >   Products   >   Proteins   >   BD-1, human recombinant protein   

BD-1, human recombinant protein

β-defensin 1, BD-1, Defensin β 1, hBD-1, HBD1, HBP1, DEFB1, HBD-1, HBP-1, DEFB101, DEFB-1, MGC51822

Product info
Primary Accession P60022
Calculated MW 5.0 kDa
Additional Info
Gene ID 1672
Gene Symbol DEFB1
Other Names β-defensin 1, BD-1, Defensin β 1, hBD-1, HBD1, HBP1, DEFB1, HBD-1, HBP-1, DEFB101, DEFB-1, MGC51822
Gene Source Human
Source E. coli
Assay&Purity SDS-PAGE; ≥98%
Assay2&Purity2 HPLC;
Recombinant Yes
Results 0.1-1 µg/ml
Target/Specificity BD-1
Application Notes Reconstitute in dH₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Format Lyophilized protein
Storage -20°C; Lyophilized from a concentrated (1 mg/ml) solution containing 20 mM PBS pH-7.4 and 130 mM sodium chloride
Citations (0)

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The Defensin family are highly similar in their protein sequence and are microbicidal & cytotoxic peptides made by neutrophils. β Defensin-1 (BD-1) is an antimicrobial peptide having the resistance of epithelial surfaces to microbial colonization. BD-1 has close proximity to Defensin α-1 and has been implicated in the pathogenesis of cystic fibrosis. Skin of patients having atopic dermatitis patients and mycosis fungoides (non-lesional and lesional) show lower human BD-1 mRNA expression and higher human BD-2 and human BD-3 mRNA expression. β Defensin is highly expressed by epithelial cells. BD-1 may play a role in the pathogenesis of severe sepsis. Variation in human BD-1 contributes to asthma diagnosis, with apparent gender-specific effects. Human BD-3 is a dimer, while Human BD-1 and Human BD-2 are monomeric. Recombinant human β Defensin-1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 47 amino acids and having a molecular mass of 5 kDa.


Liu L.,et al.Genomics 43:316-320(1997).
Zhao C.,et al.Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases.
McCray P.B. Jr.,et al.Am. J. Respir. Cell Mol. Biol. 16:343-349(1997).
Bensch K.W.,et al.FEBS Lett. 368:331-335(1995).
Kluever E.,et al.J. Pept. Res. 59:241-248(2002).

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$ 2,950.00
$ 190.00
Cat# PBV10289r-1
Availability: 5-7days
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