BMP-12/GDF-7, human recombinant protein
bone morphogenetic protein 12, BMP12, BMP 12
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | BAD07014 |
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Calculated MW | 27 kDa |
Gene ID | 151449 |
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Gene Symbol | BMP12/GDF7 |
Other Names | BMP-12/GDF-7, BMP12/GDF7, BMP 12/GDF 7, |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥98% |
Assay2&Purity2 | HPLC; ≥98% |
Recombinant | Yes |
Results | 0.2 – 2.5 µg/ml |
Target/Specificity | BMP-12/GDF-7 |
Application Notes | Reconstitute to a concentration of 0.1-1.0 mg/ml in H₂O containing BSA (50 µg BSA per 1 µg of protein). This solution can then be diluted into other aqueous buffers. |
Format | Lyophilized protein |
Storage | -20°C; Sterile filtered and lyophilized with no additives |
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Provided below are standard protocols that you may find useful for product applications.
Background
BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-12 is highly conserved across species. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation. Recombinant human BMP-12 is a 27 kDa disulfide-linked homodimer containing two 122 amino acid polypeptide chains.
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