BMP-11, human recombinant protein
bone morphogenetic protein 11, BMP11, BMP 11, Growth/Differentiation Factor-11, GDF-11, GDF11, GDF 1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O95390 |
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Calculated MW | 32.6 kDa |
Gene ID | 10220 |
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Gene Symbol | BMP11/GDF11 |
Other Names | bone morphogenetic protein 11, BMP11, BMP 11, Growth/Differentiation Factor-11, GDF-11, GDF11, GDF 11 |
Gene Source | Human |
Source | E. coli |
Assay&Purity | SDS-PAGE; ≥98% |
Assay2&Purity2 | HPLC; ≥98% |
Recombinant | Yes |
Results | 0.4-4 µg/ml |
Target/Specificity | BMP-11 |
Application Notes | Reconstitute to a concentration of 0.1-1.0 mg/ml in H₂O containing BSA (50 µg BSA per 1 µg of protein). This solution can then be diluted into other aqueous buffers. |
Format | Lyophilized protein |
Storage | -20°C; Lyophilized from 10 mM Sodium Citrate, pH 3.5. |
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Provided below are standard protocols that you may find useful for product applications.
Background
BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. Recombinant human BMP-11 is N-terminus His-tagged protein with a molecular weight of 32.6 kDa (for homodimeric) and 16.2 (for monomeric) consisting of 136 amino acid polypeptide chains.
References
Gamer L.W.,et al.Dev. Biol. 208:222-232(1999).
McPherron A.C.,et al.Nat. Genet. 22:260-264(1999).
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