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C2orf47 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8WWC4 |
| Other Accession | Q6AY04, Q8BHE8, A3KN05 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 32545 Da |
| Antigen Region | 190-219 aa |
| Gene ID | 79568 |
|---|---|
| Other Names | Uncharacterized protein C2orf47, mitochondrial, C2orf47 |
| Target/Specificity | This C2orf47 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-219 amino acids from the C-terminal region of human C2orf47. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | C2orf47 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MAIP1 {ECO:0000303|PubMed:27642048, ECO:0000312|HGNC:HGNC:26198} |
|---|---|
| Function | Promotes sorting of SMDT1/EMRE in mitochondria by ensuring its maturation (PubMed:27642048). Interacts with the transit peptide region of SMDT1/EMRE precursor protein in the mitochondrial matrix, leading to protect it against protein degradation by YME1L1, thereby ensuring SMDT1/EMRE maturation by the mitochondrial processing peptidase (PMPCA and PMPCB) (PubMed:27642048). |
| Cellular Location | Mitochondrion matrix |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of the C2orf47 protein is currently unknown.
References
Ota T., et al. Nat. Genet. 36:40-45(2004).
Hillier L.W., et al. Nature 434:724-731(2005).
Mural R.J., et al. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S., et al. BMC Genomics 8:399-399(2007).
Burkard T.R., et al. BMC Syst. Biol. 5:17-17(2011).
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