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Zebrafish adra2a Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q90WY4 |
| Reactivity | Zebrafish |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 43997 Da |
| Antigen Region | 223-256 aa |
| Other Names | Alpha-2A adrenergic receptor, Alpha-2A adrenoreceptor, Alpha-2A adrenoceptor, Alpha-2AAR, adra2a |
|---|---|
| Target/Specificity | This Zebrafish adra2a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 223-256 amino acids from the central region of zebrafish adra2a. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Zebrafish adra2a Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | adra2a {ECO:0000250|UniProtKB:P08913} |
|---|---|
| Function | Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > oxymetazoline = epinephrine > norepinephrine. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > oxymetazoline = epinephrine > norepinephrine.
References
Ruuskanen J.O.,et al.Mol. Biol. Evol. 21:14-28(2004).
Ruuskanen J.O.,et al.Br. J. Pharmacol. 144:165-177(2005).
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