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> home > Products > Primary Antibodies > Antibody Collections > Catalog Updated > NDNF Antibody (N-term)
NDNF Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | Q8TB73 |
| Other Accession | NP_078850.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 64673 Da |
| Antigen Region | 80-109 aa |
| Gene ID | 79625 |
|---|---|
| Other Names | Protein NDNF, Neuron-derived neurotrophic factor, NDNF, C4orf31 |
| Target/Specificity | This C4orf31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids of human C4orf31. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NDNF Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NDNF |
|---|---|
| Synonyms | C4orf31 |
| Function | Secretory protein that plays a role in various cellular processes (PubMed:20969804, PubMed:24706764, PubMed:31883645). Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus (PubMed:31883645). Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system (PubMed:20969804, PubMed:31883645). May also act through the regulation of growth factors activity and downstream signaling (PubMed:31883645). Also regulates extracellular matrix assembly and cell adhesiveness (By similarity). Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms (PubMed:24706764). |
| Cellular Location | Secreted |
| Tissue Location | Expressed in neurons along the gonadotropin- releasing hormone (GnRH) expressing neurons migratory route |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Promotes matrix assembly and cell adhesiveness (By similarity).
References
Utine, G.E., et al. Genet. Couns. 17(2):205-209(2006) Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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$ 150.00
$ 385.00
Cat# AP5812a
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