|Application ||WB, E|
|Other Accession||Q8BMB0, Q7ZUV7|
|Calculated MW||141468 Da|
|Antigen Region||46-75 aa|
|Other Names||Protein EMSY, EMSY, C11orf30|
|Target/Specificity||This C11orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the N-terminal region of human C11orf30.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||C11orf30 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin (PubMed:14651845). Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2 (PubMed:14651845). Mediates ligand-dependent transcriptional activation by nuclear hormone receptors (PubMed:19131338).|
|Cellular Location||Nucleus. Note=Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2.
?Esparza-Gordillo, J., et al. Nat. Genet. 41(5):596-601(2009)
?Garapaty, S., et al. J. Biol. Chem. 284(12):7542-7552(2009)
?Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)
?Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.