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Zebrafish arnt2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9DG12 |
| Reactivity | Zebrafish |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 80972 Da |
| Antigen Region | 475-501 aa |
| Gene ID | 64277 |
|---|---|
| Other Names | Aryl hydrocarbon receptor nuclear translocator 2, ARNT protein 2, zfARNT2, arnt2 {ECO:0000312|ZFIN:ZDB-GENE-001207-3} |
| Target/Specificity | This Zebrafish arnt2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 475-501 amino acids from the central region of zebrafish arnt2. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Zebrafish arnt2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | arnt2 {ECO:0000312|ZFIN:ZDB-GENE-001207-3} |
|---|---|
| Function | Transcription factor that plays a role in the development of the hypothalamo-pituitary axis. Specifically recognizes the xenobiotic response element (XRE) (By similarity). Isoform 1 acts as a transcriptional activator (PubMed:11072074). Isoform 3 acts as a transcriptional repressor (PubMed:10960127, PubMed:11072074). |
| Cellular Location | Nucleus. |
| Tissue Location | Isoform 1 and isoform 2 are most highly expressed in the brain, eye and skeletal muscle and to a lower degree in liver, heart, kidney and swim bladder. Isoform 3 is most highly expressed in the eye, forebrain, midbrain, hindbrain, skeletal muscle, gills and brain but is barely detectable in liver, heart, kidney and swim bladder. Before the pharyngula period isoform 3 is expressed throughout the entire embryo and during this period extensively in the brain and eye. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Specifically recognizes the xenobiotic response element (XRE). Isoform 1 acts as a transcriptional activator. Isoform 3 acts as a transcriptional repressor.
References
Tanguay R.L., et al. Biochim. Biophys. Acta 1494:117-128(2000).
Wang W.-D., et al. Mar. Biotechnol. 2:376-386(2000).
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