|Application ||WB, E|
|Antigen Region||19-45 aa|
|Other Names||NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3, ndufaf3|
|Target/Specificity||This DANRE ndufaf3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of DANRE ndufaf3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DANRE ndufaf3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).|
|Cellular Location||Nucleus. Mitochondrion inner membrane EMBL; BC129030; AAI29031.1; -; mRNA RefSeq; NP_001074084.1; NM_001080615.1 STRING; 7955.ENSDARP00000109973; - PaxDb; A1L1F1; - PeptideAtlas; A1L1F1; - Ensembl; ENSDART00000161432; ENSDARP00000134881; ENSDARG00000112931 Ensembl; ENSDART00000184883; ENSDARP00000156172; ENSDARG00000112931 GeneID; 791133; - KEGG; dre:791133; - CTD; 25915; - ZFIN; ZDB-GENE-070112-282; ndufaf3 eggNOG; KOG3363; Eukaryota GeneTree; ENSGT00390000018312; - InParanoid; A1L1F1; - KO; K09008; - OrthoDB; 1569969at2759; - PhylomeDB; A1L1F1; - TreeFam; TF321072; - Reactome; R-DRE-6799198; Complex I biogenesis PRO; PR:A1L1F1; - Proteomes; UP000000437; Chromosome 22 GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IBA:GO_Central CDD; cd05125; Mth938_2P1-like; 1 Gene3D; 3.40.1230.10; -; 1 InterPro; IPR036748; MTH938-like_sf InterPro; IPR034095; NDUF3 InterPro; IPR007523; NDUFAF3/AAMDC PANTHER; PTHR21192; PTHR21192; 1 Pfam; PF04430; DUF498; 1 SUPFAM; SSF64076; SSF64076; 1 2: Evidence at transcript level; Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleus; Reference proteome CHAIN 1..174 /note="NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3" /id="PRO_0000281156" SEQUENCE 174 AA; 19019 MW; 9AA83FF235F638F4 CRC64; MAAVRHLCQR TAIRLRLTCS PQSRVCVVRG HRLGPFDDEQ YRKTSVSIMQ KEASAGTVIY SYSPRGFNIN GNTVFGPCAV LPPAILQWNV GSHSDISVES LSLFYLLEPQ IEVLVLGTGA RTERLHAEVL EELKKRGIAV EVQDTPNACA TFNFLSSEKR LAAAALIPPP AGSR|
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Provided below are standard protocols that you may find useful for product applications.
Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (By similarity).
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