|Other Names||Nuclear GTPase SLIP-GC, 3.6.1.-, Speckled-like pattern in the germinal center, NUGGC, C8orf80|
|Target/Specificity||The synthetic peptide sequence is selected from aa 47-59 of HUMAN NUGGC|
|Format||Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA (PubMed:19734146). Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity).|
|Cellular Location||Nucleus speckle.|
|Tissue Location||Expressed in germinal center B-cell and in lymphomas derived from germinal center B-cell|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Plays a role as replication-related GTPase protein in germinal center B-cell.
Nusbaum C.,et al.Nature 439:331-335(2006).
Yamada S.,et al.Oncogene 23:5901-5911(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Richter K.,et al.J. Biol. Chem. 284:30652-30661(2009).
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