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Hira antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q61666 |
| Other Accession | NM_010435, NP_034565 |
| Reactivity | Human, Mouse, Rat, Rabbit, Horse, Dog |
| Predicted | Human, Mouse, Rabbit, Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 112 KDa |
| Gene ID | 15260 |
|---|---|
| Alias Symbol | AA138857, D16Ertd95e, N28177, Tuple1 |
| Other Names | Protein HIRA, TUP1-like enhancer of split protein 1, Hira, Tuple1 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Hira antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Hira antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Hira |
|---|---|
| Synonyms | Tuple1 |
| Function | Required for the periodic repression of histone gene transcription during the cell cycle (By similarity). Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. |
| Cellular Location | Nucleus. Nucleus, PML body. Note=Primarily, though not exclusively, localized to the nucleus (By similarity). Localizes to PML bodies immediately prior to onset of senescence (By similarity). Localizes specifically to the male nucleus in fertilized eggs. This localization persists from the initiation of sperm nucleus decondensation to pronucleus formation {ECO:0000250, ECO:0000269|PubMed:15922569, ECO:0000269|PubMed:9731536} |
| Tissue Location | Expressed in cerebrum, cerebellum, heart, kidney, liver, lung and spleen |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 389.00
Cat# AI11112
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