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CRP Antibody (Ascites)
Mouse Monoclonal Antibody (Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P02741 |
| Other Accession | NP_000558.2 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG3 |
| Clone/Animal Names | 506CT15.5.3 |
| Calculated MW | 25039 Da |
| Antigen Region | 194-221 aa |
| Gene ID | 1401 |
|---|---|
| Other Names | C-reactive protein, C-reactive protein(1-205), CRP, PTX1 |
| Target/Specificity | This CRP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 194-221 amino acids from human CRP. |
| Dilution | WB~~1:500~8000 |
| Format | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CRP Antibody (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CRP |
|---|---|
| Synonyms | PTX1 |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Cellular Location | Secreted. |
| Tissue Location | Found in plasma. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli.
References
Brindle, E., et al. J. Immunol. Methods 362 (1-2), 112-120 (2010) :
Lim, L.S., et al. Invest. Ophthalmol. Vis. Sci. 51(9):4458-4463(2010)
Marott, S.C., et al. J. Am. Coll. Cardiol. 56(10):789-795(2010)
Szczesny, G., et al. Arch Orthop Trauma Surg (2010) In press :
Kuhlenbaeumer, G., et al. Cerebrovasc. Dis. 30(5):476-482(2010)
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