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Calretinin Antibody

Sheep polyclonal antibody

  • WB - Calretinin Antibody AN1173
    Western blot of rat cerebellum (CB) lysate showing specific immunolabeling of the~ 29k calretinin protein.
  • IF - Calretinin Antibody AN1173
    Immunostaining of rat cerebellum showing fluorescenceof calretinin containing cells.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P47728
Reactivity Rat
Predicted Human, Mouse, Monkey
Host Sheep
Clonality polyclonal
Calculated MW 29 KDa
Additional Information
Gene ID 117059
Gene Name CALB2
Other Names Calretinin, CR, Calb2
Target/Specificity Purified guinea pig calretinin.
Dilution WB~~ 1:1000
IF~~ 1:500
Format Protein A purified sheep serum.
Antibody Specificity Specific for the ~29 kDa calretinin protein in Western blots of rat brain lysate. The antibody also works well for Immunohistochemistry on formalin or paraformaldehyde perfused rat brain tissue sections.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCalretinin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
ShippingBlue Ice
Research Areas
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Calretinin is a calcium-binding protein involved in calcium signaling. It is abundantly expressed throughout the central nervous system, retina and many other tissues. Studies have shown that calretinin may play a role in neuroprotection by buffering intracellular calcium (Lukas and Jones 1994, Weisenhorn et al., 1996). Additionally, calretinin selectively stains mesothelial cells thus making it an important marker for differentiating malignant mesothelioma from carcinomas (Attanoos et al., 2000).


Attanoos RL, Dojcinov SD, Webb R, Gibbs AR. (2000) Anti-mesothelial markers in sarcomatoid mesothelioma and other spindle cell neoplasms. Histopathology.37(3):224-31.
Isaacs KR, Winsky L, Strauss KI, Jacobowitz DM. (1995) Quadruple colocalization of calretinin, calcitonin gene-related peptide, vasoactive intestinal peptide, and substance P in fibers within the villi of the rat intestine. Cell Tissue Res., 280(3):639-51.
Lukas W, Jones KA (1994) Cortical neurons containing calretinin are selectively resistant to calcium overload and excitotoxicity in vitro. Neurosci. 61(2):307-16.
Weisenhorn DMV, Weruaga-Prieto E, Celio MR (1996) Calretinin immunoreactivity in organotypic cultures of the rat cerebral cortex: effects of serum deprivation. Exp. Brain Res. 108(1):101-112.

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$ 365.00
Cat# AN1173
Availability: 7-10 days
Bulk Size

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