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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Nicotinic Acetylcholine Receptor (nAChR) b4 Antibody   

Nicotinic Acetylcholine Receptor (nAChR) b4 Antibody

Rabbit Polyclonal Antibody

     
  • WB - Nicotinic Acetylcholine Receptor (nAChR) b4 Antibody AN1285
    Western blot of mouse habenula lysate showing specific immunolabeling of the ~52 kDa nAChRβ4 protein.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, ICC
Primary Accession Q8R493
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 55809 Da
Additional Information
Gene ID 108015
Gene Name Chrnb4
Target/Specificity Fusion protein from the cytoplasmic loop of the beta 4 subunit of rat nAChR
Dilution WB~~ 1:1000
Format Antigen Affinity Purified from Pooled Serum
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNicotinic Acetylcholine Receptor (nAChR) b4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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Research Areas
Citations (0)

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Background

Nicotinic acetylcholine receptors (nAChRs) are ionotropic, cholinergic receptors that are divided into 2 types; muscle type and neuronal type. Neuronal nAChRs are pentameric ion channels consisting of 5 identical (homopentamers) or different (heteropentamers) subunits. Heteropentameric neuronal nAChRs mediate fast synaptic transmission in the autonomic nervous system. The predominant hetero-oligomeric nAChR in the CNS contain the subunits α4β2, whereas α3β4 prevail in the PNS. However, the expression of these subunits varies not only by region but also during development (Scholze et al 2011). In the brain, β2-containing receptors greatly outnumber receptors that contain β4 (

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$ 365.00
Cat# AN1285
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