|Application ||WB, E|
|Other Accession||Q5FVK8, Q8BIX3, Q5EA92, NP_689529.1|
|Antigen Region||228-257 aa|
|Other Names||ARL14 effector protein, ARF7 effector protein, ARL14EP, ARF7EP, C11orf46|
|Target/Specificity||This C11orf46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-257 amino acids from the C-terminal region of human C11orf46.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||C11orf46 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Through its interaction with ARL14 and MYO1E, may connect MHC class II-containing cytoplasmic vesicles to the actin network and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells.|
|Tissue Location||Expressed in the immune system. EMBL; AK096287; BAC04747.1; -; mRNA EMBL; BX647617; CAI46092.1; -; mRNA EMBL; BC047775; AAH47775.1; -; mRNA CCDS; CCDS7869.1; - RefSeq; NP_689529.1; NM_152316.2 UniGene; Hs.502208; - ProteinModelPortal; Q8N8R7; - SMR; Q8N8R7; - BioGrid; 125690; 9 IntAct; Q8N8R7; 8 STRING; 9606.ENSP00000282032; - iPTMnet; Q8N8R7; - PhosphoSitePlus; Q8N8R7; - BioMuta; ARL14EP; - DMDM; 74729511; - EPD; Q8N8R7; - jPOST; Q8N8R7; - MaxQB; Q8N8R7; - PaxDb; Q8N8R7; - PeptideAtlas; Q8N8R7; - PRIDE; Q8N8R7; - ProteomicsDB; 72456; - DNASU; 120534; - Ensembl; ENST00000282032; ENSP00000282032; ENSG00000152219 GeneID; 120534; - KEGG; hsa:120534; - UCSC; uc001mso.2; human CTD; 120534; - DisGeNET; 120534; - EuPathDB; HostDB:ENSG00000152219.4; - GeneCards; ARL14EP; - H-InvDB; HIX0017336; - HGNC; HGNC:26798; ARL14EP HPA; HPA039634; - HPA; HPA048127; - MIM; 612295; gene neXtProt; NX_Q8N8R7; - OpenTargets; ENSG00000152219; - PharmGKB; PA142672291; - eggNOG; KOG4850; Eukaryota eggNOG; ENOG4111QTN; LUCA GeneTree; ENSGT00940000156586; - HOGENOM; HOG000232178; - HOVERGEN; HBG055275; - InParanoid; Q8N8R7; - OMA; QFANPGR; - OrthoDB; 1056242at2759; - PhylomeDB; Q8N8R7; - TreeFam; TF333216; - ChiTaRS; ARL14EP; human GenomeRNAi; 120534; - PRO; PR:Q8N8R7; - Proteomes; UP000005640; Chromosome 11 Bgee; ENSG00000152219; Expressed in 192 organ(s), highest expression level in secondary oocyte ExpressionAtlas; Q8N8R7; baseline and differential Genevisible; Q8N8R7; HS GO; GO:0005829; C:cytosol; IDA:HPA GO; GO:0005925; C:focal adhesion; IDA:HPA GO; GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA GO; GO:0005730; C:nucleolus; IDA:HPA GO; GO:0005634; C:nucleus; IDA:HPA GO; GO:0005886; C:plasma membrane; IDA:HPA InterPro; IPR029264; ARF7EP_C InterPro; IPR026515; ARL14EP PANTHER; PTHR23080:SF72; PTHR23080:SF72; 1 Pfam; PF14949; ARF7EP_C; 1 1: Evidence at protein level; Acetylation; Complete proteome; Cytoplasm; Isopeptide bond; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation CHAIN 1 260 ARL14 effector protein /FTId=PRO_0000251892 COMPBIAS 209 237 Cys-rich MOD_RES 1 1 N-acetylmethionine MOD_RES 183 183 Phosphoserine CROSSLNK 177 177 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) VARIANT 180 180 T -> P (in dbSNP:rs7940297) /FTId=VAR_033740 CONFLICT 88 88 K -> KK (in Ref. 2; CAI46092) CONFLICT 245 245 Q -> QK (in Ref. 2; CAI46092) SEQUENCE 260 AA; 29338 MW; 18B70E7DB57B3252 CRC64; MMDPCSVGVQ LRTTNECHKT YYTRHTGFKT LQELSSNDML LLQLRTGMTL SGNNTICFHH VKIYIDRFED LQKSCCDPFN IHKKLAKKNL HVIDLDDATF LSAKFGRQLV PGWKLCPKCT QIINGSVDVD TEDRQKRKPE SDGRTAKALR SLQFTNPGRQ TEFAPETGKR EKRRLTKNAT AGSDRQVIPA KSKVYDSQGL LIFSGMDLCD CLDEDCLGCF YACPACGSTK CGAECRCDRK WLYEQIEIEG GEIIHNKHAG|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.