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> home > Products > Primary Antibodies > Antibody Collections > mRNA transport > LUZP4 Antibody (N-term)
LUZP4 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9P127 |
| Other Accession | NP_057467.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 35937 Da |
| Antigen Region | 33-62 aa |
| Gene ID | 51213 |
|---|---|
| Other Names | Leucine zipper protein 4, Cancer/testis antigen 28, CT-28, CT28, Tumor antigen HOM-TES-85, LUZP4 |
| Target/Specificity | This LUZP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human LUZP4. |
| Dilution | IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LUZP4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LUZP4 |
|---|---|
| Function | Export adapter involved in mRNA nuclear export in cancer cells. Binds and enhances the RNA-binding activity of the nuclear RNA export factor NXF1. Can restore mRNA export function in cells compromised by loss of mRNA export adapters (PubMed:25662211). |
| Cellular Location | Nucleus. Cytoplasm Note=In nuclear speckles. Relocalizes to the cytoplasm during cell division. |
| Tissue Location | Expressed specifically in testis. Also expressed in a wide variety of cancer types, but particularly high levels of expression observed in melanoma cells. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Tureci, O., et al. Oncogene 21(24):3879-3888(2002)
Sahin, U., et al. Clin. Cancer Res. 6(10):3916-3922(2000)
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$ 150.00
$ 385.00
Cat# AP10265a
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