|Application ||WB, E|
|Other Accession||NP_001002006.1, NP_150278.2|
|Calculated MW||68804 Da|
|Antigen Region||3-32 aa|
|Other Names||Cytosolic 5'-nucleotidase 1B, cN1B, Autoimmune infertility-related protein, Cytosolic 5'-nucleotidase IB, cN-IB, NT5C1B, AIRP|
|Target/Specificity||This NT5C1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-32 amino acids from the N-terminal region of human NT5C1B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NT5C1B Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity).|
|Tissue Location||Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Cytosolic 5-prime nucleotidases, such as NT5C1B, catalyze production of adenosine, which regulates diverse physiologic processes (Sala-Newby and Newby, 2001 [PubMed 11690631]).[supplied by OMIM].
Gass, N., et al. J Affect Disord 126 (1-2), 134-139 (2010) :
Cirulli, E.T., et al. Eur. J. Hum. Genet. 18(7):815-820(2010)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Sala-Newby, G.B., et al. Biochim. Biophys. Acta 1521 (1-3), 12-18 (2001) :
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