FAM46A Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
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Primary Accession | Q96IP4 |
Other Accession | NP_060103.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 49666 Da |
Antigen Region | 89-117 aa |
Gene ID | 55603 |
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Other Names | Protein FAM46A, HBV X-transactivated gene 11 protein, HBV XAg-transactivated protein 11, FAM46A, C6orf37, XTP11 |
Target/Specificity | This FAM46A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the Central region of human FAM46A. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | FAM46A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TENT5A (HGNC:18345) |
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Function | Cytoplasmic non-canonical poly(A) RNA polymerase that catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and participates in the cytoplasmic polyadenylation (PubMed:33882302). Polyadenylates mRNA encoding extracellular matrix constituents and other genes crucial for bone mineralization and during osteoblast mineralization, mainly focuses on ER-targeted mRNAs (By similarity). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:D3Z5S8}. |
Tissue Location | Widely expressed, with preferential expression observed in the retina compared to other ocular tissues (PubMed:12054608). Also expressed in osteoblasts (PubMed:29358272) |
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Provided below are standard protocols that you may find useful for product applications.
References
Barragan, I., et al. Ann. Hum. Genet. 72 (PT 1), 26-34 (2008) :
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Cui, J., et al. Zhejiang Da Xue Xue Bao Yi Xue Ban 35(4):354-359(2006)
Cui, J., et al. Clin. Chim. Acta 368 (1-2), 155-159 (2006) :
Lim, J., et al. Cell 125(4):801-814(2006)
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