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LRRC34 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IZ02 |
| Other Accession | NP_001166250.1, NP_699184.2 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 51277 Da |
| Antigen Region | 154-182 aa |
| Gene ID | 151827 |
|---|---|
| Other Names | Leucine-rich repeat-containing protein 34, LRRC34 |
| Target/Specificity | This LRRC34 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-182 amino acids from the Central region of human LRRC34. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LRRC34 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LRRC34 |
|---|---|
| Function | Highly expressed in stem cells where it may be involved in regulation of pluripotency. In embryonic stem cells (ESCs), important for normal expression of the pluripotency regulators POU5F1/OCT4 and KLF4. Also important for expression of the ectodermal marker gene NES and the endodermal marker gene GATA4. Promotes stem cell proliferation in vitro. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q9DAM1}. Nucleus, nucleolus {ECO:0000250|UniProtKB:Q9DAM1}. Cytoplasm {ECO:0000250|UniProtKB:Q9DAM1}. Note=As stem cells differentiate, translocates from the nucleolus to the nucleus and then to the cytoplasm. Colocalizes with NPM1 and NCL in the nucleolus {ECO:0000250|UniProtKB:Q9DAM1} |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 365.00
$ 140.00
Cat# AP10603c
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