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TOR2A Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TOR2A Antibody (Center) AP12178c
    TOR2A Antibody (Center) (Cat. #AP12178c) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the TOR2A antibody detected the TOR2A protein (arrow).
  • IHC-P - TOR2A Antibody (Center) AP12178c
    TOR2A Antibody (Center) (Cat. #AP12178c)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TOR2A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5JU69
Other Accession Q6AYR4, NP_001127902.1, NP_569726.2
Reactivity Human
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35714 Da
Antigen Region 194-221 aa
Additional Information
Gene ID 27433
Other Names Torsin-2A, Torsin family 2 member A, Torsin-related protein 1, TOR2A, TORP1
Target/Specificity This TOR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-221 amino acids from the Central region of human TOR2A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTOR2A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TOR2A
Synonyms TORP1
Cellular Location Endoplasmic reticulum lumen.
Tissue Location Isoform 1 is expressed ubiquitously, except in cardiac and endothelial tissues.
Research Areas
Citations (0)

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Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis; it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.


O'Farrell, C.A., et al. Neuroscience 164(3):1127-1137(2009)
Sato, K., et al. Peptides 29(12):2203-2207(2008)
Watanabe, T., et al. Hypertens. Res. 31(3):463-468(2008)
Wang, Z., et al. Eur. J. Pharmacol. 539(3):145-150(2006)
Humphray, S.J., et al. Nature 429(6990):369-374(2004)

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$ 325.00
$ 109.00
Cat# AP12178c
Availability: In Stock
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