ODF2L Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
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Primary Accession | Q9ULJ1 |
Other Accession | Q0VBY1, NP_001171694.1, NP_065780.2 |
Reactivity | Human |
Predicted | Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 73728 Da |
Antigen Region | 543-572 aa |
Gene ID | 57489 |
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Other Names | Outer dense fiber protein 2-like, ODF2L, KIAA1229 |
Target/Specificity | This ODF2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 543-572 amino acids from the C-terminal region of human ODF2L. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ODF2L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ODF2L (HGNC:29225) |
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Function | Acts as a suppressor of ciliogenesis, specifically, the initiation of ciliogenesis. |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes to centrioles in proliferative cells and basal bodies in ciliated cells (PubMed:17485331). Disappears during ciliogenesis but reappears, albeit at a lower levels once ciliogenesis has completed (PubMed:28775150) [Isoform 6]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Disappears during ciliogenesis but reappears, albeit at a lower levels once ciliogenesis has completed. |
Tissue Location | Mainly expressed in trachea and testis. Not detected in bone marrow, bladder, leukocytes. Only weakly detected in tongue, stomach, brain and ovaries. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ODF2L belongs to the ODF2 family. The specific function of this protein remains unknown.
References
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
Nagase, T., et al. DNA Res. 6(5):337-345(1999)
Bonaldo, M.F., et al. Genome Res. 6(9):791-806(1996)
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