|Application ||WB, E|
|Other Accession||B5MC32, NP_001073942.1|
|Calculated MW||53743 Da|
|Antigen Region||383-411 aa|
|Other Names||Major facilitator superfamily domain-containing protein 2B, MFSD2B|
|Target/Specificity||This MFSD2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-411 amino acids from the C-terminal region of human MFSD2B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MFSD2B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cation-dependent lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets (PubMed:29045386). Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology (By similarity). Does not transport lysophosphatidylcholine (LPC) (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Note=Localizes to the cell membrane and intracellular membranes|
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Provided below are standard protocols that you may find useful for product applications.
Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009) :
Angers, M., et al. Biochem. J. 416(3):347-355(2008)
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