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DUSP15 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9H1R2 |
| Other Accession | Q8R4V2, Q6PGN7 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 31882 Da |
| Antigen Region | 17-44 aa |
| Gene ID | 128853 |
|---|---|
| Other Names | Dual specificity protein phosphatase 15, VH1-related member Y, Vaccinia virus VH1-related dual-specific protein phosphatase Y, DUSP15, C20orf57, VHY |
| Target/Specificity | This DUSP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-44 amino acids from the N-terminal region of human DUSP15. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DUSP15 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DUSP15 (HGNC:16236) |
|---|---|
| Function | May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6 (PubMed:22792334). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Highly expressed in testis (PubMed:15138252). Expressed in brain; up-regulated in patients with multiple sclerosis gray matter lesions (PubMed:22792334). |
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Provided below are standard protocols that you may find useful for product applications.
Background
DUSP15 belongs to the non-receptor class of the protein-tyrosine phosphatase family. This protein has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase.
References
Alonso, A., et al., J. Biol. Chem. 279(31):32586-32591 (2004).
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