|Application ||IHC-P, WB, E|
|Other Accession||Q8R4V2, Q6PGN7|
|Calculated MW||31882 Da|
|Antigen Region||17-44 aa|
|Other Names||Dual specificity protein phosphatase 15, VH1-related member Y, Vaccinia virus VH1-related dual-specific protein phosphatase Y, DUSP15, C20orf57, VHY|
|Target/Specificity||This DUSP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-44 amino acids from the N-terminal region of human DUSP15.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DUSP15 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6 (PubMed:22792334).|
|Tissue Location||Highly expressed in testis (PubMed:15138252). Expressed in brain; up-regulated in patients with multiple sclerosis gray matter lesions (PubMed:22792334)|
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Provided below are standard protocols that you may find useful for product applications.
DUSP15 belongs to the non-receptor class of the protein-tyrosine phosphatase family. This protein has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase.
Alonso, A., et al., J. Biol. Chem. 279(31):32586-32591 (2004).
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