CDC2L6 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | Q9BWU1 |
Other Accession | Q8BWD8 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 56802 Da |
Antigen Region | 253-285 aa |
Gene ID | 23097 |
---|---|
Other Names | Cyclin-dependent kinase 19, CDC2-related protein kinase 6, Cell division cycle 2-like protein kinase 6, Cell division protein kinase 19, Cyclin-dependent kinase 11, Death-preventing kinase, CDK19, CDC2L6, CDK11, KIAA1028 |
Target/Specificity | This CDC2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-285 amino acids from the Central region of human CDC2L6. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CDC2L6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CDK19 |
---|---|
Synonyms | CDC2L6, CDK11, KIAA1028 |
Cellular Location | Cytoplasm. Cytoplasm, perinuclear region. Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
CDC2L6 is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
References
Malumbres,M., et.al. Nat. Cell Biol. 11 (11), 1275-1276 (2009)
Loyer,P., et.al., J. Biol. Chem. 283 (12), 7721-7732 (2008)
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