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KCTD12 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - KCTD12 Antibody (Center) AP9273c
    Western blot analysis of KCTD12 Antibody (Center) (Cat. #AP9273c) in T47D cell line lysates (35ug/lane). KCTD12 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - KCTD12 Antibody (Center) AP9273c
    Formalin-fixed and paraffin-embedded human brain tissue reacted with KCTD12 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
  • FC - KCTD12 Antibody (Center) AP9273c
    KCTD12 Antibody (Center) (Cat. #AP9273c) flow cytometric analysis of T47D cells (right histogram) compared to a negative control (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, IHC-P, WB, E
Primary Accession Q96CX2
Other Accession Q6WVG3
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 35701 Da
Antigen Region 242-269 aa
Additional Information
Gene ID 115207
Other Names BTB/POZ domain-containing protein KCTD12, Pfetin, Predominantly fetal expressed T1 domain, KCTD12, C13orf2, KIAA1778, PFET1
Target/Specificity This KCTD12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-269 amino acids from the Central region of human KCTD12.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCTD12 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCTD12
Synonyms C13orf2, KIAA1778, PFET1
Function Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).
Cellular Location Presynaptic cell membrane. Postsynaptic cell membrane
Tissue Location Present in a variety of fetal organs, with highest expression levels in the cochlea and brain and, in stark contrast, is detected only at extremely low levels in adult organs, such as brain and lung.
Research Areas
Citations (0)
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References

Drenos,F., et.al., Hum. Mol. Genet. 18 (12), 2305-2316 (2009) Suehara,Y., et.al., Clin. Cancer Res. 14 (6), 1707-1717 (2008) Cauchi,S., et.al., J. Mol. Med. 86 (3), 341-348 (2008)

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$ 365.00
$ 140.00
Cat# AP9273c
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