|Application ||IHC-P, WB, E|
|Other Accession||D4A6D8, Q8K377, A1A4H9|
|Calculated MW||58641 Da|
|Antigen Region||88-117 aa|
|Other Names||Leucine-rich repeat transmembrane neuronal protein 1, LRRTM1|
|Target/Specificity||This LRRTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-117 amino acids from the Central region of human LRRTM1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LRRTM1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein|
|Tissue Location||Predominantly expressed in forebrain regions including thalamus and cerebral cortex.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
LRRTM1 may play a role during the development of specific forebrain structures by influencing neuronal differentiation and connectivity, with a possible role in intracellular trafficking within axons.
Francks, C. Laterality 14(1):11-16(2009)
Crow, T.J., et al. Laterality 14(1):3-10(2009)
McManus, C., et al. Laterality 14(1):1-2(2009)
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