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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CCT7 Antibody (monoclonal) (M01)   

CCT7 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a partial recombinant CCT7.

     
  • WB - CCT7 Antibody (monoclonal) (M01) AT1430a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.07 KDa) .
    detail
  • WB - CCT7 Antibody (monoclonal) (M01) AT1430a
    CCT7 monoclonal antibody (M01), clone 1D6. Western Blot analysis of CCT7 expression in human pancreas.
    detail
  • WB - CCT7 Antibody (monoclonal) (M01) AT1430a
    CCT7 monoclonal antibody (M01), clone 1D6. Western Blot analysis of CCT7 expression in PC-12((Cat # AT1430a )
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  • WB - CCT7 Antibody (monoclonal) (M01) AT1430a
    CCT7 monoclonal antibody (M01), clone 1D6. Western Blot analysis of CCT7 expression in 293.
    detail
  • WB - CCT7 Antibody (monoclonal) (M01) AT1430a
    CCT7 monoclonal antibody (M01), clone 1D6 Western Blot analysis of CCT7 expression in HL-60 ( (Cat # AT1430a )
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  • WB - CCT7 Antibody (monoclonal) (M01) AT1430a
    CCT7 monoclonal antibody (M01), clone 1D6. Western Blot analysis of CCT7 expression in Raw 264.7((Cat # AT1430a )
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  • WB - CCT7 Antibody (monoclonal) (M01) AT1430a
    CCT7 monoclonal antibody (M01), clone 1D6. Western Blot analysis of CCT7 expression in NIH/3T3((Cat # AT1430a )
    detail
  • WB - CCT7 Antibody (monoclonal) (M01) AT1430a
    CCT7 monoclonal antibody (M01), clone 1D6. Western Blot analysis of CCT7 expression in K-562 ( (Cat # AT1430a )
    detail
  • WB - CCT7 Antibody (monoclonal) (M01) AT1430a
    Western Blot analysis of CCT7 expression in transfected 293T cell line by CCT7 monoclonal antibody (M01), clone 1D6.

    Lane 1: CCT7 transfected lysate(59.4 KDa).
    Lane 2: Non-transfected lysate.
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  • E - CCT7 Antibody (monoclonal) (M01) AT1430a
    Detection limit for recombinant GST tagged CCT7 is approximately 0.3ng/ml as a capture antibody.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q99832
Other Accession BC019296
Reactivity Human, Mouse, Rat
Host mouse
Clonality Monoclonal
Isotype IgG1 kappa
Clone Names 1D6
Calculated MW 59367 Da
Additional Information
Gene ID 10574
Other Names T-complex protein 1 subunit eta, TCP-1-eta, CCT-eta, HIV-1 Nef-interacting protein, CCT7, CCTH, NIP7-1
Target/Specificity CCT7 (AAH19296, 425 a.a. ~ 528 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsCCT7 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)
citation

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Background

This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6.

References

Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes. Mukherjee K, et al. BMC Evol Biol, 2010 Mar 1. PMID 20193073.Defining the human deubiquitinating enzyme interaction landscape. Sowa ME, et al. Cell, 2009 Jul 23. PMID 19615732.A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. Goudreault M, et al. Mol Cell Proteomics, 2009 Jan. PMID 18782753.The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1. Zebol JR, et al. Int J Biochem Cell Biol, 2009 Apr. PMID 18775504.PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4. Chen GI, et al. J Biol Chem, 2008 Oct 24. PMID 18715871.

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$ 350.00
Cat# AT1430a
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