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PHF20 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9BVI0 |
|---|---|
| Clone Names | 101008133 |
| Gene ID | 51230 |
|---|---|
| Other Names | PHD finger protein 20, Glioma-expressed antigen 2, Hepatocellular carcinoma-associated antigen 58, Novel zinc finger protein, Transcription factor TZP, PHF20, C20orf104, GLEA2, HCA58, NZF, TZP |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PHF20 |
|---|---|
| Synonyms | C20orf104, GLEA2, HCA58, NZF, TZP |
| Function | Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine- dependent p53/TP53 stabilization and up-regulation after DNA damage. |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed in heart, kidney, liver, lung, pancreas, placenta, spleen and testis. Not expressed in brain, skeletal muscle, colon, ovary, prostate, small intestine and thymus. Expressed in colon and ovary cancer cell lines while it is not expressed in the respective normal tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
PHF20 is possible a transcription factor.
References
Bankovic, J., et al. Lung Cancer 67(2):151-159(2010)Heisel, S.M., et al. PLoS ONE 3 (5), E2164 (2008) :Olsen, J.V., et al. Cell 127(3):635-648(2006)Pallasch, C.P., et al. Int. J. Cancer 117(3):456-459(2005)Dou, Y., et al. Cell 121(6):873-885(2005)
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