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MEPE Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9NQ76
Clone Names 100324224
Peptide ID 100324224
Additional Information
Gene ID 56955
Other Names Matrix extracellular phosphoglycoprotein, Osteoblast/osteocyte factor 45, OF45, MEPE
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Promotes renal phosphate excretion and inhibits intestinal phosphate absorption (PubMed:14962809, PubMed:19005008). Promotes bone mineralization by osteoblasts and cartilage mineralization by chondrocytes (PubMed:18162525, PubMed:19998030, PubMed:22766095). Regulates the mineralization of the extracellular matrix of the craniofacial complex, such as teeth, bone and cartilage (By similarity). Promotes dental pulp stem cell proliferation and differentiation (PubMed:22341070).
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Expressed by osteoblasts (PubMed:10945470, PubMed:11414762, PubMed:15108058). Expressed by stem cells in dental pulp (PubMed:15153459). Expressed by mesenchymal cells in dental papilla and dental pulp (PubMed:18547474, PubMed:22341070) Expressed in teeth, specifically in decidious dentin (PubMed:20581062). Expressed in ondotoblasts (PubMed:12489176) Expressed in salivary glands (PubMed:15329369). Secreted from oncogenic hypophosphatemic tumors (PubMed:11414762)
Research Areas
Citations (0)

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MEPE seems to play a role in mineralization.


Boskey, A.L., et al. Calcif. Tissue Int. 86(1):42-46(2010)Pereira, R.C., et al. Bone 45(6):1161-1168(2009)Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)Rivadeneira, F., et al. Nat. Genet. 41(11):1199-1206(2009)Marks, J., et al. J. Am. Soc. Nephrol. 19(12):2313-2320(2008)

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Cat# BP12395a
Availability: Back Order
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