|Other Names||Syntaxin-8, STX8|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER.|
|Cellular Location||Membrane; Single-pass type IV membrane protein. Note=Preferentially associated with the early endosome. To a lesser extent, also present in late endosome, the plasma membrane and coated pits (By similarity)|
|Tissue Location||Highly expressed in heart. Also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas|
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Provided below are standard protocols that you may find useful for product applications.
The gene is a member of the syntaxin family. The encodedprotein is involved in protein trafficking from early to lateendosomes via vesicle fusion and exocytosis. A related pseudogenehas been identified on chromosome 12. Alternative splicing resultsin multiple transcript variants.
Sebastiani, P., et al. Science (2010) In press :Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Henckaerts, L., et al. Clin. Gastroenterol. Hepatol. 7(9):972-980(2009)Weersma, R.K., et al. Am. J. Gastroenterol. 104(3):630-638(2009)He, Y., et al. J. Lipid Res. 50(3):398-404(2009)
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