|Other Names||Signal-transducing adaptor protein 2, STAP-2, Breast tumor kinase substrate, BRK substrate, STAP2, BKS|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes the substrate of breast tumor kinase, anSrc-type non-receptor tyrosine kinase. The encoded proteinpossesses domains and several tyrosine phosphorylation sitescharacteristic of adaptor proteins that mediate the interactionslinking proteins involved in signal transduction pathways.Alternative splicing results in multiple transcript variants.
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)Sekine, Y., et al. J. Immunol. 183(12):7966-7974(2009)Sekine, Y., et al. Biochem. Biophys. Res. Commun. 384(2):187-192(2009)Ikeda, O., et al. Biochem. Biophys. Res. Commun. 384(1):71-75(2009)Ikeda, O., et al. Mol. Cell. Biol. 28(16):5027-5042(2008)
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