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PWP2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q15269 |
|---|---|
| Clone Names | 110617090 |
| Gene ID | 5822 |
|---|---|
| Other Names | Periodic tryptophan protein 2 homolog, PWP2, PWP2H |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | PWP2 (HGNC:9711) |
|---|---|
| Synonyms | PWP2H |
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre- ribosomal RNA by the RNA exosome. |
| Cellular Location | Nucleus, nucleolus |
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Provided below are standard protocols that you may find useful for product applications.
Background
PWP2H belongs to the WD repeat PWP2 family.
References
Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002)Nagamine, K., et al. Genomics 42(3):528-531(1997)Nagamine, K., et al. Biochem. Biophys. Res. Commun. 235(1):185-190(1997)Lafreniere, R.G., et al. Genome Res. 6(12):1216-1226(1996)Lalioti, M.D., et al. Genomics 35(2):321-327(1996)
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