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PWP2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q15269 |
| Other Accession | Q8BU03, NP_005040.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 102452 Da |
| Antigen Region | 567-596 aa |
| Gene ID | 5822 |
|---|---|
| Other Names | Periodic tryptophan protein 2 homolog, PWP2, PWP2H |
| Target/Specificity | This PWP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-596 amino acids from the Central region of human PWP2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PWP2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PWP2 (HGNC:9711) |
|---|---|
| Synonyms | PWP2H |
| Function | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre- ribosomal RNA by the RNA exosome. |
| Cellular Location | Nucleus, nucleolus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
PWP2H belongs to the WD repeat PWP2 family.
References
Scherl, A., et al. Mol. Biol. Cell 13(11):4100-4109(2002)
Nagamine, K., et al. Genomics 42(3):528-531(1997)
Nagamine, K., et al. Biochem. Biophys. Res. Commun. 235(1):185-190(1997)
Lafreniere, R.G., et al. Genome Res. 6(12):1216-1226(1996)
Lalioti, M.D., et al. Genomics 35(2):321-327(1996)
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