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ADAMTS18 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8TE60
Clone Names 90723135
Additional Information
Gene ID 170692
Other Names A disintegrin and metalloproteinase with thrombospondin motifs 18, ADAM-TS 18, ADAM-TS18, ADAMTS-18, 3424-, ADAMTS18, ADAMTS21
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8906b was selected from the C-term region of human ADAMTS18. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADAMTS18
Synonyms ADAMTS21
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Expressed in fetal lung, liver, and kidney and in adult brain, prostate, submaxillary gland, and endothelium
Research Areas
Citations (0)
citation

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Background

ADAMTS18 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This protein has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor.

References

Zeng,W., et.al., Biochim. Biophys. Acta 1760 (3), 517-524 (2006)Jin,H., et.al., Oncogene 26 (53), 7490-7498 (2007)

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$ 277.78
Cat# BP8906b
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