CDC123 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O75794 |
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Clone Names | 90723027 |
Gene ID | 8872 |
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Other Names | Cell division cycle protein 123 homolog, Protein D123, HT-1080, PZ32, CDC123, C10orf7, D123 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8913b was selected from the C-term region of human CDC123. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CDC123 |
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Synonyms | C10orf7, D123 |
Function | ATP-dependent protein-folding chaperone for the eIF2 complex (PubMed:35031321, PubMed:37507029). Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (By similarity). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q62834}. |
Tissue Location | Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CDC123 is required for S phase entry of the cell cycle (By similarity).
References
Lango Allen,H., et.al., Diabetes 59 (1), 266-271 (2010)Schulze,M.B., et.al., Diabetes Care 32 (11), 2116-2119 (2009)
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