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CDC123 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O75794
Clone Names 90723027
Additional Information
Gene ID 8872
Other Names Cell division cycle protein 123 homolog, Protein D123, HT-1080, PZ32, CDC123, C10orf7, D123
Target/Specificity The synthetic peptide sequence used to generate the antibody AP8913b was selected from the C-term region of human CDC123. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDC123
Synonyms C10orf7, D123
Function ATP-dependent protein-folding chaperone for the eIF2 complex (PubMed:35031321, PubMed:37507029). Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q62834}.
Tissue Location Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis.
Research Areas
Citations (0)
citation

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Background

CDC123 is required for S phase entry of the cell cycle (By similarity).

References

Lango Allen,H., et.al., Diabetes 59 (1), 266-271 (2010)Schulze,M.B., et.al., Diabetes Care 32 (11), 2116-2119 (2009)

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$ 277.78
Cat# BP8913b
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