CDC123 Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, FC, IP |
|---|---|
| Primary Accession | O75794 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | C10orf7; CDC123; Cell division cycle 123; D123; HT 1080; PZ32; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 39135 Da |
| Dilution | WB 1:500~1:2000 IP 1:50 FC 1:50 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human CDC123 |
| Description | Required for S phase entry of the cell cycle. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | CDC123 |
|---|---|
| Synonyms | C10orf7, D123 |
| Function | ATP-dependent protein-folding chaperone for the eIF2 complex (PubMed:35031321, PubMed:37507029). Binds to the gamma subunit of the eIF2 complex which allows the subunit to assemble with the alpha and beta subunits (By similarity). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q62834}. |
| Tissue Location | Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes with the highest expression in testis. |

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