|Other Names||Guanine nucleotide-binding protein subunit beta-like protein 1, G protein subunit beta-like protein 1, DGCRK3, WD repeat-containing protein 14, WD40 repeat-containing protein deleted in VCFS, WDVCF, GNB1L, GY2, KIAA1645, WDR14|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP8967c was selected from the Center region of human GNB1L. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||GY2, KIAA1645, WDR14|
|Tissue Location||Ubiquitous. Highly expressed in heart, liver, skeletal muscle, kidney, spleen, thymus and pancreas. Detected at low levels in lung, placenta and brain|
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Provided below are standard protocols that you may find useful for product applications.
GNB1L is a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart.
Funke,B., et.al., Genomics 73 (3), 264-271 (2001)Collins,J.E., et.al., Genome Biol. 5 (10), R84 (2004)
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