GNB1L Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q9BYB4 |
Reactivity | Rat, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 35618 Da |
Gene ID | 54584 |
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Other Names | Guanine nucleotide-binding protein subunit beta-like protein 1, G protein subunit beta-like protein 1, DGCRK3, WD repeat-containing protein 14, WD40 repeat-containing protein deleted in VCFS, WDVCF, GNB1L, GY2, KIAA1645, WDR14 |
Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | GNB1L (HGNC:4397) |
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Synonyms | GY2, KIAA1645, WDR14 |
Function | Acts as a critical regulator of DNA damage response (DDR) signaling via specifically regulating phosphatidylinositol 3-kinase- related protein kinase (PIKK) family proteins. |
Cellular Location | Cytoplasm. Nucleus. Note=Localizes mainly in cytosol and to a lesser extent in the nucleus. |
Tissue Location | Ubiquitous. Highly expressed in heart, liver, skeletal muscle, kidney, spleen, thymus and pancreas. Detected at low levels in lung, placenta and brain. |
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