SDS Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P20132 |
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Clone Names | 90723113 |
Gene ID | 10993 |
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Other Names | L-serine dehydratase/L-threonine deaminase, SDH, L-serine deaminase, L-threonine dehydratase, TDH, SDS, SDH |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9041a was selected from the N-term region of human SDS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SDS |
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Synonyms | SDH |
Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
SDS encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver.
References
Yamada,T., et.al., Biochim. Biophys. Acta 1780 (5), 809-818 (2008)Szaflik,J.P., et.al., Exp. Eye Res. 86 (4), 647-652 (2008)
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