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> home > Products > Primary Antibodies > Signal Transduction > SDS/Serine dehydratase Polyclonal Antibody
SDS/Serine dehydratase Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | P20132 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 35 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human SDS/Serine dehydratase |
| Epitope Specificity | 201-300/328 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the serine/threonine dehydratase family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008] |
| Gene ID | 10993 |
|---|---|
| Other Names | L-serine dehydratase/L-threonine deaminase, SDH, 4.3.1.17, L-serine deaminase, L-threonine dehydratase, TDH, 4.3.1.19, SDS, SDH |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | SDS |
|---|---|
| Synonyms | SDH |
| Function | Catalyzes the pyridoxal-phosphate-dependent dehydrative deamination of L-threonine and L-serine to ammonia and alpha- ketobutyrate and pyruvate, respectively. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P09367}. |
| Tissue Location | Predominantly expressed in the perivenous regions of the liver. |
Research Areas
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$ 385.00
Cat# AP57894
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