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DIPA Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q15834 |
|---|---|
| Clone Names | 81006090 |
| Gene ID | 11007 |
|---|---|
| Other Names | Coiled-coil domain-containing protein 85B, Hepatitis delta antigen-interacting protein A, Delta-interacting protein A, CCDC85B, DIPA |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9120c was selected from the Center region of human DIPA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CCDC85B |
|---|---|
| Synonyms | DIPA |
| Function | Functions as a transcriptional repressor (PubMed:17014843). May inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth (PubMed:17873903). May function in adipocyte differentiation, negatively regulating mitotic clonal expansion (By similarity). Plays a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (By similarity). |
| Cellular Location | Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell junction, adherens junction |
| Tissue Location | Widely expressed including liver. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
DIPA functions as a transcriptional repressor. It may inhibit the activity of CTNNB1 in a TP53-dependent manner and thus regulate cell growth. It may function in adipocyte differentiation, negatively regulating mitotic clonal expansion.
References
Bezy,O., et.al., J. Biol. Chem. 280 (12), 11432-11438 (2005)Du,X.,et.al., Exp. Mol. Pathol. 81 (3), 184-190 (2006)
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